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Table 2 Time schedule of regular study visits

From: Trichuris suis ova in relapsing-remitting multiple sclerosis and clinically isolated syndrome (TRIOMS): study protocol for a randomized controlled trial

  Screening Random (month 0) Tel.V1 -6 (week 0, 2, 4, 6, 8, 10, 16, 20, 28, 32, 40, 44) ± 3 days V1 (month 3) ± 10 days V2 (month 6) ± 10 days V3 (month 9) ± 10 days V4 (month 12) ± 10 days V5 (month 15) ± 10 days (optional) V6 (month 18) ± 10 days (optional)
Informed consent x         
In/exclusion criteria x x        
Randomization   x        
Demographic data x         
Pregnancy test x         
Confirmation of MS diagnosis x         
Relapse history x x   x x x x x x
Medical history x x   x x x x x x
Physical examination x    x x x x   x
Vital signs x x   x x x x   x
Weight x       x   x
MSFC x       x   x
EDSS x   x x x x x   x
Safety lab x    x x x x   x
Immunological sampling   x   x x x x   x
MRI x     x x x optional optional
AE/SAE     x x x x x x
Questionnaires (fatigue, depression) x x    x x x x x
Drug supply   x x x x x    
Drug account      x   x