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Table 1 Major patient inclusion and exclusion criteria for the PERFECT trial (ClinicalTrials.gov Identifier: NCT00950274)

From: Validating intramyocardial bone marrow stem cell therapy in combination with coronary artery bypass grafting, the PERFECT Phase III randomized multicenter trial: study protocol for a randomized controlled trial

Patient inclusion criteria

Exclusion criteria

Coronary artery disease with indication for CABG and previous myocardial infarction

Emergency operation

LVEF between 25% and 50% measured by cardiac MRI

Acute myocardial infarction within last 2 weeks

Akinetic/hypokinetic/hibernating left ventricular areas localized by cardiac stress MRI

Resuscitation in combination with ventricular arrhythmias within the last 14 days before treatment

Absence of any moderate to severe valvular heart disease requiring concomitant valve replacement or reconstruction

Active cancer, organ transplantation, end-stage renal disorder

Informed consent of the patient

Infection (CRP ≥ 20 mg/L, temperature ≥38.5 °C)

Age between 18 and 79 years

Contraindication for MRI

  1. CRP, c-reactive protein; LVEF, left ventricular ejection fraction; MRI, magnet resonance imaging.