Table 1 Outcome measures in the PINCER Trial

Primary outcome measures

The proportion of patients in each practice:

1. With a history of peptic ulcer being prescribed non-selective non-steroidal anti-inflammatory drugs

2. With a history of asthma being prescribed beta-blockers

3. Aged 75 years and older receiving long-term prescriptions for angiotensin-converting enzyme inhibitors or loop diuretics without a recorded assessment of renal function and electrolytes in the preceding 15 months.

4. Proportions of women with a past medical history of venous or arterial thrombosis who have been prescribed the combined oral contraceptive pill

Secondary outcome measures

5. Patients receiving methotrexate for at least three months who have not had a recorded full blood count and/or liver function test within the previous three months

6. Patients receiving warfarin for at least three months who have not had a recorded check of their international normalized ratio within the previous 12 weeks

7. Patients receiving lithium for at least three months who have not had a recorded check of their lithium levels within the previous three months

8. Patients receiving amiodarone for at least six months who have not had a thyroid function test within the previous six months

9. Patients receiving prescriptions of methotrexate without instructions that the drug should be taken weekly

10. Patients receiving prescriptions of amiodarone for at least one month who were receiving a dose of more than 200 mg per day.