Table 1
Characteristic | Older drugs | Newer drugs | Difference (95% CI) | P |
|---|---|---|---|---|
Number | 69 | 71 | ||
Anthropometrics | ||||
Women, n [%] | 33 (47.8) | 42 (59.2) | 0.23 | |
Age, years | 50.5 ± 8.6 | 50.9 ± 9.2 | 0.4 (−2.6 to 3.4) | 0.78 |
Weight, kg | 80.8 ± 14.6 | 76.9 ± 14.7 | −4.0 (−8.9 to 0.9) | 0.11 |
Height, cm | 167.8 ± 7.8 | 166.4 ± 9.0 | −1.2 (−4.1 to 1.6) | 0.39 |
Body mass index, kg/m2 | 28.7 ± 4.6 | 27.8 ± 5.1 | −0.9 (−2.5 to 0.8) | 0.30 |
Waist circumference, cm | 94.5 ± 13.9 | 92.9 ± 11.5 | −1.6 (−5.9 to 2.7) | 0.47 |
Sitting blood pressure | ||||
Systolic, mm Hg | 154.2 ± 11.0 | 153.7 ± 11.8 | −0.5 (−4.3 to 3.3) | 0.80 |
Diastolic, mm Hg | 92.2 ± 9.4 | 90.8 ± 10.3 | −1.4 (−4.7 to 1.9) | 0.41 |
Heart rate, beats/minute | 74.0 ± 9.5 | 73.1 ± 10.3 | −0.9 (−4.2 to 2.4) | 0.59 |
Standing blood pressure | ||||
Systolic, mm Hg | 154.9 ± 13.8 | 154.1 ± 12.8 | −0.7 (−5.2 to 3.7) | 0.74 |
Diastolic, mm Hg | 97.1 ± 9.5 | 97.5 ± 10.2 | 0.4 (−2.9 to 3.7) | 0.82 |
Heart rate, beats/minute | 81.6 ± 9.5 | 80.6 ± 10.3 | −1.0 (−4.7 to 2.7) | 0.60 |
Lifestyle | ||||
Past smokers, n [%] | 9 (13.2) | 13 (18.3) | 0.48 | |
Current smokers, n [%] | 3 (4.4 ) | 1 (1.4 ) | 0.35 | |
Sniffing tobacco, n [%] | 0 (0.0 ) | 0 (0.0 ) | 1.00 | |
Current drinkers, n [%] | 22 (32.4) | 22 (31.0) | 1.00 | |
Blood measurements | ||||
Hemoglobin, mg/dL | 12.9 ± 1.7 | 12.8 ± 1.7 | −0.1 (−0.7 to 0.5) | 0.74 |
Hematocrit, % | 39.0 ± 5.0 | 38.8 ± 5.7 | −0.2 (−2.0 to 1.7) | 0.86 |
Glucose, mmol/L | 5.1 ± 0.9 | 4.9 ± 0.7 | −0.2 (−0.4 to 0.1) | 0.19 |
Cholesterol, mmol/L | 4.9 ± 1.1 | 4.8 ± 1.2 | −0.0 (−0.4 to 0.4) | 0.86 |
Creatinine, μmol/L | 86.1 ± 20.1 | 90.9 ± 34.5 | 4.8 (−4.7 to 14.3) | 0.32 |
ECG measurements | ||||
Sokolow-Lyon index, mm | 28.1 ± 7.7 | 29.8 ± 7.2 | 1.7 (−0.8 to 4.2) | 0.18 |
Cornell index, mm × msec | 1818 ± 836 | 1771 ± 594 | −48 (−290 to 194) | 0.70 |