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Table 2 Main methodological characteristics of schizophrenia drug trials published in Italy from 1948 to 2009 (n = 81 studies)

From: Forty-five years of schizophrenia trials in Italy: a survey

  n % (95% CI)
Sample size   
Min-20 22 27.1 (17.8-38.1)
21-40 32 39.5 (28.8-50.9)
40-max 27 33.3 (23.2-44.6)
Length of follow-up (weeks)   
Unclear 10 12.3 (6.08-21.5)
2-4 30 24.6 (15.7-35.5)
5-12 21 25.9 (16.8-36.8)
13+ 20 24.6 (15.7-35.5)
Randomization   
Randomized, no details 51 62.9 (51.5-73.4)
Randomized with details 7 8.6 (3.54-16.9)
Unclear 23 28.4 (18.9-39.5)
Blinding   
Single blind 6 7.4 (2.76-15.4)
Double blind 47 58.0 (46.5-68.9)
Unclear 28 34.5 (24.3-45.9)
Outcome measures (n)   
1-5 33 40.7 (29.9-52.2)
6-15 35 43.2 (32.2-54.6)
16-60 13 16.0 (8.83-25.8)
Patient flow diagram   
Yes 2 2.4 (0.30-8.63)
No 79 97.6 (91.3-99.6)
  1. CI confidence interval