Table 1 Prospective studies assessing complication rates in untreated distal deep vein thrombosis (DVT) patients
Author/year | Population | Sample size | Diagnostic method | Duration of follow-up for primary endpoint | VTE complication rate |
|---|---|---|---|---|---|
Schwarz et al. 2010 [22] | Low-risk ambulatory patients with isolated calf muscle thrombus | 53 | CUS | 3 months | 2/53 = 3.77% |
Palareti et al. 2010 [21] | Symptomatic outpatients | 65 | CUS | 3 months | 5/64 = 7.8% |
Macdonald et al. 2003 [19] | Mostly symptomatic surgical and medical inpatients (68.6%) with isolated calf muscle vein thrombus | 135 | CUS | 3 months | 4/135 = 3% |
Schwarz et al. 2001 [23] | Symptomatic outpatients with isolated calf muscle vein thrombosis | 32 | CUS | 3 months | 8/32 = 25% |
Lohr et al. 1995 [18] | Mostly symptomatic surgical and medical inpatients (59.4%) | 192 | CUS | 4 weeks | 21/169 = 12.4% |
Oishi et al. 1994 [20] | Asymptomatic postoperative total hip replacement/total knee replacement patients | 41 | CUS | 12 months | 7/41 = 17.1% |
Lagerstedt et al. 1985 [17] | Symptomatic medical patients | 28 | Isotopic uptake confirmed by ascending phlebography | 90 days | 8/28 = 29% |