Table 3 Acute BiV pacing studies after cardiac surgery.
Investigator | Study title | Sample | Result |
|---|---|---|---|
Pokushalov [20], 2010. | CABG with CRT in patients with ischaemic heart failure and dyssynchrony. | N = 178 EF ≤ 35% QRS > 120 | Reduced mortality with CRT, p = 0.006, reduced LOS and improved CI at 48 hours, p < 0.001. |
Eberhardt [30], 2009. | BiV pacing after CABG in patients with reduced LV function. | N = 94 EF ≤ 40% | No significant difference between BiV and other pacing modes on haemodynamics or LOS. |
Hanke [24], 2009. | BiV pacing after cardiopulmonary bypass in patients with reduced LV function. | N = 21 EF < 35% QRS > 120 | BiV superior to DDD(RV) pacing but not DDD(LV) or AAI pacing. |
Evonich [31], 2008. | Temporary BiV pacing in cardiac patients with severely reduced LV function. | N = 40 EF ≤ 30% | No significant change in LOS or haemodynamic function with BiV. |
Hamad [32], 2009. | Acute haemodynamic effect of CRT in patients with poor LV function during surgery. | N = 11 QRS > 130 EF ≤ 35% | Optimised (VV) BIV pacing improved haemodynamics (p = 0.03) v RV pacing. |
Muehlschlegel [33], 2008. | Temporary BiV pacing after CABG in patients with reduced ejection fraction. | N = 10 EF < 50% QRS > 120 | Significant improvement in cardiac output with BiV v DDD(RV or LV). |
Dzemali [34], 2008. | Impact of different pacing modes on LV function following CABG. | N = 80 EF ≤ 35% | Patients with dilated LV (mean 65 v 52mm) more likely to respond to BiV, p < 0.001. |