Exclusion criteria |
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1. Left main coronary artery stenosis >50% |
2.High-grade stenosis (>75%) of the proximal left anterior descending artery |
3. Stenosis with a minimum diameter of <2 mm |
4. Acute coronary syndromes or recent myocardial infarction within the past 2 months |
5. LV-EF ≤40% |
6. Significant valvular heart disease |
7. Pregnancy |
8. Contraindication for application of adenosine: |
 AV block II and III° |
 Sick sinus syndrome |
 Long QT |
 Asthma bronchiale |
9. Limitation of physical activity for reasons not due to coronary artery disease |
10. Life expectancy <1 year |
11 Substance abuse (drug or alcohol) problem within the previous 6 months |