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Table 1 Primary and secondary endpoints

From: Impact of different exercise training modalities on the coronary collateral circulation and plaque composition in patients with significant coronary artery disease (EXCITE trial): study protocol for a randomized controlled trial

Primary Change in CBI after 4 weeks of treatment
Secondary 1. Change in plaque morphology by virtual
  histology at 4 weeks as assessed by IVUS
  2. Change in myocardial perfusion at 4 weeks and
  12 months as assessed by adenosine MRI
  3. MACE at 1, 3, 6 and 12 months
  4. Hospitalization due to cardiovascular causes
  5. Change in atherosclerotic parameters (hs-CRP,
  ADMA, endostatin, EPC, ox LDL, cytokines,
  adiponectine), lipid status and glucose status
  6. Change in exercise capacity (ergospirometry) and
  V02 peak