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Table 1 Time schedule of regular study visits and outcome parameters

From: Efficacy of Vitamin D Supplementation in Multiple Sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial

  Screening (Week -2) V0 (Baseline) ± 7 days V1(Month 1) ± 7 days V2 (Month 3) ± 7 days V3 (Month 6) ± 14 days V4 (Month 9) ± 14 days V5 (Month 12) ± 14 days V6 (Month 18) ± 21 days Follow up (Month 24) ± 8 weeks (optional)
Informed consent         
In/exclusion criteria        
Randomization          
Evaluation of relapses
Concomitant medication
Physical examination        
Vital signs
MSFC      
EDSS      
ECG         
Safety lab  
Immunology blood sampling        
MRI      
OCT      
Visual contrast parameters      
Quantitative motor function tests      
Questionnaires (fatigue, depression, QoL)      
Cognitive testing (SDMT, FST)       
Drug account     
Adverse event reporting