Baseline parameter/variable | |
---|---|
The level of fibrinogen before intervention defined by Clauss method (g/L) | |
Presence of hypofibrinogenaemia before intervention defined by Clauss method (<2 g/L) and equivalent functional fibrinogen (TEG) MA (< 14 mm or according to validation in this study). | |
Hypocoagulability prior to intervention measured with standard TEG: R-time >8 min or alpha angle <55° or MA <50 mm or LY30 >8 % | |
Crystalloids used prior to intervention (ml) | |
Colloids used prior to intervention (ml) | |
The use of tranexamic acid prior to intervention (yes/no) | |
Mode of delivery | Caesarean section |
Vaginal delivery | |
Post vaginal procedure | Intended manual removal of placenta |
Manual exploration of the uterus due to continuous bleeding after the birth of placenta | |
Estimated blood loss before intervention (ml)* | |
Primary cause of PPH: | |
TRAUMA of the birth canal: paravaginal haematoma, cervical laceration, vaginal laceration, perineal laceration, uterine rupture | |
Retained TISSUE: Retained placental tissue, Percrete or accrete placenta | |
Impaired THROMBOSIS: disseminated intravascular coagulation, placental abruption, severe pre-eclampsia | |
Reduced TONE of uterus: uterine atony | |
Weight of parturient (kg) (because dose of fibrinogen = 2 g/BW kg) | |
Units of allogenic blood transfusion transfused prior to intervention (numbers of units) | |
Bleeding duration (from start of bleeding to intervention) (min.) | |
Time from birth to intervention (min.) | |
Baseline haemoglobin (measured before intervention) (mmol/L or g/dL) | |
Method of anaesthesia: general versus regional anaesthesia |