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Table 3 Patient-based measures in treatment group

From: The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments

  Mean SD Range
BDI-II score 8.2 7.6 1 - 25
MSIS-29 Physical score 66.3 9.5 51 - 80
MSIS Psychological score 20.7 5.2 11 - 27
EDSS 6.1 0.3 5.5 - 6.5
ACE-R score 92.4 5.9 85 - 100
MSFC (total) z-score -1.5 1.4 -5.4 - -0.4
MSFC (arm) z-score -1.5 0.6 -2.7 - -0.7
MSFC (leg) z-score -2.0 4.1 -13.7 - -0.3
MSFC (cognitive) z-score -0.9 1.1 -2.1 - 1.2
Normalised brain volume (ml) 1486 75 1361 - 1586
T 2 lesion volume (cm 3 ) 40.5 30.1 3.4 - 99.5
T 1 lesion volume (cm 3 ) 10.2 9.5 0.6 - 31.3
  1. BDI-II = Beck's Depression Inventory II; MSIS-29 = Multiple Sclerosis Impact Score (29 - item); EDSS = expanded Kurtzke disability status scale; ACE-R = Addenbrooke's Cognitive Examination (Revised)