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The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments

  • Peter Connick1, 2, 4Email author,
  • Madhan Kolappan3,
  • Rickie Patani1, 2,
  • Michael A Scott3,
  • Charles Crawley3,
  • Xiao-Ling He2,
  • Karen Richardson3,
  • Kelly Barber3,
  • Daniel J Webber2,
  • Claudia AM Wheeler-Kingshott3,
  • Daniel J Tozer3,
  • Rebecca S Samson3,
  • David L Thomas5,
  • Ming-Qing Du6,
  • Shi L Luan6,
  • Andrew W Michell1,
  • Daniel R Altmann7,
  • Alan J Thompson8,
  • David H Miller3,
  • Alastair Compston1 and
  • Siddharthan Chandran2, 9
Contributed equally

Received: 5 November 2010

Accepted: 2 March 2011

Published: 2 March 2011

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
5 Nov 2010 Submitted Original manuscript
7 Feb 2011 Reviewed Reviewer Report - Letizia Mazzini
7 Feb 2011 Reviewed Reviewer Report - Franca Fagioli
18 Feb 2011 Author responded Author comments - Peter Connick
Resubmission - Version 2
18 Feb 2011 Submitted Manuscript version 2
2 Mar 2011 Editorially accepted
2 Mar 2011 Article published 10.1186/1745-6215-12-62

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Dept. of Clinical Neurosciences, University of Cambridge
Anne MacLaren Laboratory for Regenerative Medicine, University of Cambridge
NMR Research Unit, Dept. of Neuroinflammation, UCL Institute of Neurology
Blood & Marrow Transplant Unit, Addenbrooke's Hospital
The Advanced Magnetic Resonance Imaging Group, University College London
Dept. of Pathology, University of Cambridge
Medical Statistics Unit, London School of Hygiene and Tropical Medicine
Dept of Brain Repair & Rehabilitation, University College London
Euan MacDonald Centre, University of Edinburgh