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Subjects > 18 years of age
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Contraindication for use of ARB
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Either gender
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Urgent need for revascularization procedure
|
|
First episode of acute MI
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Severe heart failure (NYHA IV or need for inotropic support)
|
|
Typical pain lasting ≥ 20 minutes
|
Persistent (>1 hour) severe hypotension (systolic blood pressure < 90 mmHg)
|
|
ST elevation of more than 1 mm in at least 2 separate leads on the ECG
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Refractory or potentially lethal arrhythmias
|
|
An echocardiographic LV EF < 50%
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Hemodynamically significant right ventricular infarction
|
|
Optimal recording of echocardiographic imaging of apical chamber views
|
Congenital heart disease
|
|
Patients who provide written informed consent
|
Primary valvular disease, severer than mild degree
|
| |
Idiopathic hypertrophic cardiomyopathy
|
| |
Concomitant inflammatory cardiomyopathy
|
| |
Significant renal dysfunction (serum creatinine 2.5 mg/dl)
|
| |
Significant hepatic dysfunction (serum transaminase more than 3 times normal)
|
| |
Anemia (hemoglobin < 10 mg/mL or 6 mmol/L)
|
| |
Psychiatric disorders, alcohol or drug abuse
|
| |
Life expectancy is less than 1 year
|
| |
Participation in any other pharmacological study within 2 months
|
| |
Refusal or inability to provide informal consent
|
