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Table 1 Patients in- and exclusion criteria

From: The effect of C1-esterase inhibitor on systemic inflammation in trauma patients with a femur fracture - The CAESAR study: study protocol for a randomized controlled trial

Inclusion criteria Exclusion criteria
Multi-trauma patient
ISS* ≥ 18
Femur fracture
Age 18-80 years
Informed consent
Congenital C1-inhibitor deficiency
Use of immune suppressants
Known hypersensitivity for blood
Fixation of the femoral fracture with external fixation or osteosynthesis
  1. *ISS = Injury Severity Score