Table 1 Statistical power (1-β) of a trial comparing nitric oxide with placebo (n = 90 patients per group) for the adjunctive therapy of severe malaria, using longitudinal Ang-2 levels as primary outcome
| Standard Deviation of Ang-2 levels at admission (% of mean) | Difference in rate of change of Ang-2 between groups | ||
|---|---|---|---|
| 30% change (810 pg/mL/day) | 40% change (1080 pg/mL/day) | 50% change (1350 pg/mL/day) | |
| 40 | 82% | 97% | 99% |
| 50 | 66% | 89% | 98% |
| 80 | 42% | 60% | 80% |