Table 1 Study schedule

Eligibility assessed by paramedic from routine clinical data

x

Study discussed and verbal informed consent/assent obtained by paramedic

x

Randomisation

x

Further study information provided and written informed consent/assent obtained by hospital research team

x

Appropriateness to continue study medication reviewed by hospital team

x

Review of medical records to collect baseline stroke details and medical history

X

Blood pressure measurements

x

x

x

x

National Institute of Health Stroke Scale

x

x

x

Barthel ADL Index

(pre-stroke)

x

Barthel ADL Index

(post-stroke)

x

Modified Rankin Scale

(pre-stroke)

x

Modified Rankin Scale

(post-stroke)

x

Blood test for renal function

x

Review of medical records to record concomitant blood pressure medications

x

Treatment with study medication

x

x

x

x

x

x

x

Review of study medication dosage

x

Adverse Events

x

x

x

x

x

x

x