Table 1 List of difficulties that may be encountered and potential solutions
| Difficulties that may be encountered | Potential solutions |
|---|---|
| Regulatory bodies with different standards |
Loco- regional recognition of international standards Adaptation of international standards to local realities |
| Administrative bottle necks | Creation of research managing bodies within the administration |
| Financial bottle necks | Budgets should be drawn after extensive ground work |
| Multiple languages | The local languages should be considered from the conception stages |
| Patient compensation options | Ethical, feasible options should be employed after consulting with patient associations, other researchers and health personnel |
| Interviewer compensation modalities | All the options should be discussed openly with the interviewers during the preliminary stages and contracts established |
| Inadequate interviewer competence | Training and capacity building |
| Different ages for legal consent | Country specific age of legal consent must be taken into account when drafting the protocol |
| No dedicated administrative officer | An experienced administrative officer should be hired |
