Table 5 Total number of events required, e, and total sample size, n, for detecting various effect sizes for Event M (distant metastasis)
From: Analysis and design of randomised clinical trials involving competing risks endpoints
Variables | Cause-specific hazard | Subdistribution hazard | ||||
|---|---|---|---|---|---|---|
| Â | csHR | e | n | subHR | e | n |
Nodal status (Absent, Present) | 0.40 | 38 | 153 | 0.39 | 38 | 231 |
Treatment (CRT, RT) | 0.43 | 45 | 209 | 0.43 | 45 | 274 |
Tumour size (1, 2-4) | 0.71 | 268 | 1209 | 0.75 | 379 | 2304 |