Skip to main content

Table 1 Group characteristics.

From: Fluvastatin in the first-line therapy of acute coronary syndrome: results of the multicenter, randomized, double-blind, placebo-controlled trial (the FACS-trial)

 

Fluvastatin

N = 78

Placebo

N = 78

P

Demographical data

   

Age (years; mean ± SD)

60.9 ± 11.5

63.2 ± 11.3

ns.

Gender

  

ns.

   Male

70.5

65.4

 

   Female

29.5

34.6

 

Weight (kg; mean ± SD)

84.1 ± 13.2

82.7 ± 14.9

ns.

Smoking status

  

ns.

   Current smoker

42.3

50.0

 

   Non-smoker

43.6

39.7

 

   Former smoker

14.1

10.3

 

History

   

IHD

16.7

25.6

ns.

MI

5.1

10.3

ns.

PCI

1.3

5.1

ns.

CABG

0

1.3

ns.

Diabetes

17.9

20.5

ns.

Hypercholesterolemia

11.5

11.5

ns.

Hypertension

51.3

51.3

ns.

Stroke

3.8

2.6

ns.

PVD

2.6

2.6

ns.

Clinical data

   

Heart rate (bpm; mean ± SD)

76.1 ± 18.1

72.2 ± 16.5

ns.

SBP (mmHg; mean ± SD)

138.4 ± 29.2

141.1 ± 25.2

ns.

DBP (mmHg; mean ± SD)

81.9 ± 17.4

80.8 ± 18.0

ns.

Acute coronary syndrome type

  

ns.

   STE ACS

60.3

69.2

 

   Non-STE ACS

39.7

30.8

 

Duration of symptoms (Hrs; mean ± SD)

10.1 ± 8.9

8.0 ± 5.9

ns.

Killip class

  

ns.

   Killip I

88.5

87.2

 

   Killip II

9.0

11.5

 

   Killip III

1.3

0

 

   Killip IV

1.3

1.3

 

Total cholesterol at admission (mmol/L; mean ± SD)

5.5 ± 1.3

5.4 ± 1.1

ns.

Troponin I at admission (μg/L; mean ± SD)

14.7 ± 29.1

8.3 ± 14.1

ns.

Peak troponin I (μg/L; mean ± SD)

78.3 ± 110.8

78.7 ± 93.9

ns.

LV ejection fraction (mean ± SD)

48.0 ± 11.4

49.0 ± 10.9

ns.

Therapy

   

Coronary angiography

98.7

98.7

ns.

Coronary intervention

87.2

91.0

ns.

   PCI

75.6

87.2

0.098

   CABG

11.5

3.8

0.130

ASA

98.7

98.7

ns.

IIb/IIIa inhibitors

5.1

5.1

ns.

UFH/LMWH

82.1

84.6

ns.

Beta-blockers

88.5

88.5

ns.

Diuretics

6.4

16.7

0.077

Clopidogrel

71.8

84.6

0.080

ACE inhibitors

66.7

69.2

ns.

Vyšš í odborná škola

53

52

+1

  1. Values are expressed in per cent or as indicated. IHD, ischemic heart disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass surgery; PVD, peripheral vascular disease; SBP, systolic blood pressure; DBP, diastolic blood pressure; STE, ST-segment elevation on ECG; ACS, acute coronary syndrome; LV, left ventricle; PCI, percutaneous coronary intervention; CABG, coronary artery bypass surgery; ASA, acetylsalicylic acid; UFH, unfractionated heparin; LMWH, low-molecular-weight heparin; ACE, angiotensin-converting enzyme.