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Table 1 Characteristics of available data in completed but unpublished trials*

From: A systematic review of clinical trials of pharmacological interventions for acute ischaemic stroke (1955-2008) that were completed, but not published in full

 

Beneficial (n = 56)

n (%)

Harmful (n = 7)

n (%)

Neutral (n = 37)

n (%)

Results

   

   Final results

54 (96.4)

6 (85.7)

36 (97.3)

   Interim results

2 (3.6)

1 (14.3)

1 (2.7)

   Clinical outcomes

40 (71.4)

7 (100)

32** (86.5)

   Non-clinical outcomes

16 (28.6)

0 (0)

4 (10.8)

Statistical significance

   

   Statistics reported

24 (42.9)

1 (14.3)

7 (18.9)

   Statistics not reported

32 (57.1)

6 (85.7)

30 (81.1)

Nature of results

   

   Quantitative

31 (55.4)

7 (100)

13 (35.1)

   Qualitative

25 (44.6)

0 (0)

24 (64.9)

  1. *Only 100 trials are included in the table as 20 did not report any results and 5 did not report results separately for each treatment group and were classified as unable to analyse.
  2. ** One trial reported results in the medical press, but the outcome measure was not described.
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Trials

ISSN: 1745-6215