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Table 1 Reported treatment practice of clinicians in specialist CF centres

From: Feasibility study to inform the design of a randomised controlled trial to eradicate Pseudomonas aeruginosa infection in individuals with Cystic Fibrosis

   Yes No
Is the treatment of a new growth of P aeruginosa the same as the first ever isolationa 33/41 (80%) 8/41 (20%)
Routine treatment of patients who present with their first growth of P aeruginosa b Oral ciprofloxacin for 3 weeks and nebulised colistin for 3 months 21/29 (72%) 8/29 (28%)
  Oral ciprofloxacin and nebulised colistin for 3 months 10/22 (45%) 12/22 (55%)
  IV antibiotics for 2 weeks and nebulised colistin for 3 months 4/18(22%) 14/18 (78%)
  Other 9/22 (41%) 13/22 (59%)
Is the first or a new P aeruginosa isolation ever treated with IV antibiotics and nebulised colistin rather than oral ciprofloxacin and nebulised colistin? 38/42 (90%) 4/42 (10%)
Likely to treat first or new growth of P aeruginosa with IV antibiotics whenb The patient is clinically unwell 35/35 (100%) 0/35 (0%)
  The patient has had a previous culture of P aeruginosa 13/24 (54%) 11/24 (46%)
  The patient has reduced lung function 28/31 (90%) 3/31 (10%)
  Other reason 14/21 (67%)c 7/21 (33%)
  1. a1 respondent did not complete this question
  2. bNo responses were compulsory for this question and clinicians were able to select more than one option
  3. c 5 other reasons related to clinical deterioration; 3 to ciprofloxacin resistance and 2 to patient preference/adherence