Table 2 Power estimates for the full cohort analysis in which the treatment effect is diluted; d denotes the proportion of subjects with zero or multiple genetic variants in whom there is a difference between the predicted initial doses
d | Treatment Effect | Power |
|---|---|---|
0.7 | 3.84 | 65% |
0.8 | 4.39 | 77% |
0.9 | 4.94 | 86% |
1.0 (Undiluted) | 5.49 | 93% |