Inclusion criteria | Exclusion criteria |
---|---|
• Age ≥ 18 years | • Presence of medical conditions putting the individual patient at increased risk for not tolerating liver resection: |
• Elective hepatic resection due to any reason | - Liver cirrhosis (Child-Pugh B or C) |
• American Society of Anaesthesiologists (ASA) score I to III [26] | - (Hereditary) coagulopathy |
• Written informed consent | • Presence of medical conditions putting the individual patient at increased risk of not tolerating at least one of this trial's study interventions: |
- Severe heart disease (e.g. severe coronary artery disease requiring intervention, cardiac insufficiency NYHA stage IV) [16] | |
- Pulmonary hypertension | |
- Renal insufficiency (serum creatinine > 2 mg/dl or > 177 μmol/l; conversion factor 88.4 or requiring dialysis) | |
- Uncorrected electrolyte imbalance | |
• Atrial fibrillation | |
• For female patients: pregnancy or lactation | |
• Technical impossibility of hepatic resection | |
• Participation in other clinical trials or observation period of competing trials interfering with the endpoints of this trial | |
• Former participation in the clinical trial | |
• Suspected lack of compliance | |
• Impaired mental state or language problems |