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Table 4 Overview of costs with all patients included and without one extreme value in each group (in euro).

From: Cost-minimization analysis in a blind randomized trial on small-incision versus laparoscopic cholecystectomy from a societal perspective: sick leave outweighs efforts in hospital savings

  Laparoscopic cholecystectomy Small-incision cholecystectomy Difference in costs
(per patient)
significance
All patients included (intention-to-treat) (n = 120) (n = 137)   
Direct costs 305760 452654   
(per patient)     
- Outpatients clinic related 2548 3304 -756 P = 0,006*
(per patient)     
- Operation theatre related     
(per patient)     
- Admittance related 54293 62627   
(per patient) 452 457 -5 P = 0.640
- Complications related     
Indirect costs 133406 123404   
(per patient) 1112 901 211 P < 0.001*
Total costs 67972 81707   
(per patient)     
  566 596 -30 P = 0.342
  50089 184917   
  (n = 50) (n = 51)   
  172005 155024   
  3440 3040 400 P = 0.315
  477765 607678   
  3981 4436 -454 P = 0.737
Without one outlier in each group (n = 119) (n = 136)   
Direct 272584 282683   
(per patient) 2291 2079 212 P = 0.006*
- Outpatient clinic related 53980 62273   
(per patient) 454 458 -4 P = 0.669
- Operation theatre related 130796 121856 203 P < 0.001*
(per patient) 1099 896   
- Admittance related 67421 81131   
(per patient) 567 597 -30 P = 0.346
- Complications related 20388 17423   
Indirect (n = 50) (n = 51)   
  172005 155024   
(per patient) 3440 3040 400 P = 0.315
Total costs 444589 437706   
(per patient) 3736 3218 518 P = 0.034*
  1. * significant difference
  2. Negative differences in costs favour the laparoscopic procedure and positive differences in costs favour the small-incision technique.