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Table 4 Per protocol analysis of primary and secondary endpoints

From: Intravenous fluid restriction after major abdominal surgery: a randomized blinded clinical trial

  Restricted (n = 18) Standard (n = 25) Absolute Risk Reduction (95% confidence interval)
Primary endpoint    
Postoperative hospital stay (days), mean (SD) 7.9 (2.4) 7.3 (3.0)  
   Median (IQR) 7.0 (6.0–10.0) 7.0 (5.5–8.0) 0.337*
Secondary endpoints    
Postoperative complications 4 6 -0.018 (-0.273 to 0.237)
- Major complications 1 3 -0.064 (-0.230 to 0.101)
   - Re-admission 1 3  
- Minor complications 3 0 0.047 (-0.168 to 0.261)
   - Wound infection 3 0  
Gastric function    
- First flatus (days) 2.5 (1.2) 2.8 (1.5)  
   Median (IQR) 3 (1.3–3) 3 (1–4) 0.569*
- First defecation (days) 3.5 (1.2) 3.3 (1.6)  
   Median (IQR) 4 (2.8–4) 4 (2–5) 0.958*
- Removal nasogastric tube (days) 2.1 (1.2) 1.8 (1.2)  
   Median (IQR) 2 (1–3) 1(1–2) 0.471*
- Removal of epidural catheter (days) 3.5 (1.3) 3.6 (1.3)  
   Median (IQR) 4 (3–4) 4 (3–4) 0.707*
- Removal of IV catheter (days) 3.9 (1.1) 3.8 (1.3)  
   Median (IQR) 4 (3–5) 4 (3–5) 0.801*
- Normal diet (days) 3.8 (1.6) 3.6 (1.7)  
   Median (IQR) 4 (2–5) 3 (3–4) 0.577*
  1. * = p-values according to Mann-Whitney U test