Baseline clinical characteristics
| | | |
Age, years
|
63.25 ± 9.78
|
65.09 ± 9.40
|
0.45
|
Sex (male/female)
|
20/25
|
34/11
|
0.005
|
Body mass index, kg/m2
|
28.56 ± 4.81
|
27.85 ± 4.13
|
0.45
|
Time since diagnosis of DM, years
|
10.11 ± 8.50
|
9.82 ± 7.57
|
0.86
|
Systolic blood pressure, mmHg
|
156.05 ± 19.9
|
151.95 ± 18.4
|
0.34
|
Diastolic blood pressure, mmHg
|
82.63 ± 7.60
|
81.22 ± 7.14
|
0.39
|
Ejection fraction, %
|
49.45 ± 10.99
|
46.83 ± 14.15
|
0.37
|
Medications
| | | |
Aspirin, n(%)
|
37(82.2%)
|
36(80%)
|
1.00
|
ACE-inhibitors/ARB, n(%)
|
32(71.1%)
|
30(66.7%)
|
0.82
|
β-blockers, n(%)
|
29(64.4%)
|
35(77.8%)
|
0.24
|
Nitrates, n(%)
|
30(66.7%)
|
30(66.7%)
|
1.00
|
Diuretics, n(%)
|
23(51.1%)
|
19(42.2%)
|
0.52
|
Statins, n(%)
|
28(62.2%)
|
17(37.8%)
|
0.034
|
Digitals, n(%)
|
6(13.3%)
|
6(13.3%)
|
1.00
|
Baseline laboratory values
| | | |
Serum creatinine, mg/dL
|
1.736 ± 0.42
|
1.736 ± 0.17
|
1.00
|
Serum urea nitrogen, mg/dL
|
60.56 ± 28.37
|
58.64 ± 28.94
|
0.75
|
Creatinine clearance, mL/min
|
42.76 ± 11.97
|
43.97 ± 11.91
|
0.63
|