Table 1 Characteristics of included articles (n = 303) and RCTs described in these articles (n = 319)*
From: Dealing with heterogeneity of treatment effects: is the literature up to the challenge?
| Characteristic | Articles Represented | # RCTs Included |
|---|---|---|
| Journal of publication | ||
| Annals | 30 (10) | 30 (9) |
| BMJ | 43 (14) | 47 (15) |
| JAMA | 45 (15) | 50 (16) |
| Lancet | 97 (32) | 101 (32) |
| NEJM | 88 (29) | 91 (29) |
| Year of publication | ||
| 1994 | 86 (28) | 91 (29) |
| 1999 | 102 (34) | 106 (33) |
| 2004 | 115 (38) | 122 (38) |
| Medical condition under study | ||
| Cardiovascular | 69 (23) | 74 (23) |
| Infectious Disease | 62 (20) | 70 (22) |
| Cancer | 41 (14) | 42 (13) |
| Psychiatry/Neurology | 25 (8) | 25 (8) |
| Other | 106 (35) | 108 (34) |
| First author's study region | ||
| North America | 115 (38) | 121 (38) |
| Other | 188 (62) | 198 (62) |
| Study design | ||
| Parallel | - | 304 (95) |
| Crossover | - | 15 (5) |
| Analysis reported | ||
| HTE analysis | - | 92 (29) |
| Subgroup without statistical comparison | - | 88 (28) |
| None | - | 139 (44) |
| Sample size | 262 (101 – 708) | |
| - | [6–41,000] |
