Table 1 Characteristics of included articles (n = 303) and RCTs described in these articles (n = 319)*
From: Dealing with heterogeneity of treatment effects: is the literature up to the challenge?
Characteristic | Articles Represented | # RCTs Included |
|---|---|---|
Journal of publication | Â | Â |
   Annals | 30 (10) | 30 (9) |
   BMJ | 43 (14) | 47 (15) |
   JAMA | 45 (15) | 50 (16) |
   Lancet | 97 (32) | 101 (32) |
   NEJM | 88 (29) | 91 (29) |
Year of publication | Â | Â |
   1994 | 86 (28) | 91 (29) |
   1999 | 102 (34) | 106 (33) |
   2004 | 115 (38) | 122 (38) |
Medical condition under study | Â | Â |
   Cardiovascular | 69 (23) | 74 (23) |
   Infectious Disease | 62 (20) | 70 (22) |
   Cancer | 41 (14) | 42 (13) |
   Psychiatry/Neurology | 25 (8) | 25 (8) |
   Other | 106 (35) | 108 (34) |
First author's study region | Â | Â |
   North America | 115 (38) | 121 (38) |
   Other | 188 (62) | 198 (62) |
Study design | Â | Â |
   Parallel | - | 304 (95) |
   Crossover | - | 15 (5) |
Analysis reported | Â | Â |
   HTE analysis | - | 92 (29) |
   Subgroup without statistical comparison | - | 88 (28) |
   None | - | 139 (44) |
Sample size |  | 262 (101 – 708) |
|  | - | [6–41,000] |