Table 1 Summary of main outcome measures used in the trial

1

Patients with a history of peptic ulcerwho have been prescribed a non-selective NSAID

2

Patients with asthmawho have been prescribed a beta-blocker

3

Patients aged 75 years and older who have been prescribed an ACE inhibitor or a loop diuretic long-term who have not had a computer-recorded check of their renal function and electrolytes in the previous 15 months

4

Proportions of women with a past medical history of venous or arterial thrombosis who have been prescribed the combined oral contraceptive pill

5

Patients receiving methotrexate for at least three months who have not had a recorded full blood count and/or liver function test within the previous three months

6

Patients receiving warfarin for at least three months who have not had a recorded check of their INR within the previous 12 weeks

7

Patients receiving lithium for at least three months who have not had a recorded check of their lithium levels within the previous three months

8

Patients receiving amiodarone for at least six months who have not had a thyroid function test within the previous six months

9

Patients receiving prescriptions of methotrexate without instructions that the drug should be taken weekly

10

Patients receiving prescriptions of amiodarone for at least one month who are receiving a dose of more than 200 mg per day