| |
ICON4
|
RE01
|
|---|
|
one-sided sig.
|
e
I
|
%
|
ρ
|
e
I
|
%
|
ρ
|
|
level at stage 1
| |
err.
| | |
err.
| |
|
0.5
|
75
|
0.04
|
0.27
|
53
|
3.18
|
0.27
|
|
0.4
|
97
|
0.20
|
0.29
|
69
|
4.58
|
0.31
|
|
0.3
|
125
|
0.03
|
0.36
|
88
|
1.08
|
0.34
|
|
0.2
|
162
|
0.26
|
0.39
|
114
|
0.26
|
0.39
|
|
0.1
|
221
|
0.12
|
0.44
|
155
|
0.46
|
0.46
|
- e
I
gives the number of control arm events for the significance level at stage 1, % err. gives the percentage of trials out of 5000 which were stopped, ρ gives the correlation between the test statistic at stage 1 on the intermediate outcome and at the final analysis on the primary outcome
