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Table 1 Risk categories and LDL-C (mg/dL) goal

From: Study protocol: Couples Partnering for Lipid Enhancing Strategies (CouPLES) – a randomized, controlled trial

Risk Category

LDL-C Goal

High: CHD and risk equivalents*

<100

Medium: No CHD, ≥ 2 risk factors**

<130

Low: No CHD, 0–1 risk factor

<160

  1. LDL-C: low-density lipoprotein cholesterol. CHD: coronary heart disease.
  2. *Risk equivalents: diabetes, clinical forms of atherosclerotic disease, and multiple risk factors that confer a 10-year risk for CHD > 20% according to the Framingham risk score. **Risk factors: hypertension (blood pressure ≥ 140/90 mmHg or on antihypertensive medication), cigarette smoking, high-density lipoprotein cholesterol < 40 mg/dL, age (men ≥ 45 years, women ≥ 55 years), and family history of premature coronary heart disease (present in male first degree relative < 55 years or female first degree relative < 65 years).
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ISSN: 1745-6215