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Figure 2 | Current Controlled Trials in Cardiovascular Medicine

Figure 2

From: Effect of increased convective clearance by on-line hemodiafiltration on all cause and cardiovascular mortality in chronic hemodialysis patients – the Dutch CONvective TRAnsport STudy (CONTRAST): rationale and design of a randomised controlled trial [ISRCTN38365125]

Figure 2

Sequential analysis. Boundaries for a double sequential triangular test with α = 0.05, power 0.80 and hazard ratio 0.75. Z is the observed number of events in the control group minus the expected number of events given treatment equivalence. V is approximately equal to a quarter of the number of events observed.

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