Enzyme estimates of infarct size correlate with functional and clinical outcomes in the setting of ST-segment elevation myocardial infarction

Table 2 ESCALAT and PRIME trials: correlations of enzymes with LVEF- and SPECT-determined infarct size

	Peak CK	Peak CK-MB	CK AUC	CK-MB AUC
LVEF	r = -0.30	r = -0.26	r = -0.28	r = -0.22
	P = 0.0354	P = 0.0599	P = 0.0508	P = 0.1117
	n = 50	n = 51	n = 50	n = 51
SPECT	r = 0.65	r = 0.64	r = 0.63	r = 0.58
	P < 0.0001	P < 0.0001	P < 0.0001	P < 0.0001
	n = 115	n = 116	n = 115	n = 116

AUC: Area-under-the-curve; CK: creatine kinase, ESCALAT: Efegatran and Streptokinase to Canalize Arteries Like Accelerated Tissue plasminogen activator, LVEF: left ventricular ejection fraction, PRIME: Prompt Reperfusion In Myocardial infarction Evolution, SPECT: single-photon emission computed tomography

ISSN: 1745-6215