Table 1 Hypothetical Illustration of Informative Noncompliance
Start of Study Year | Compliant Patients | Â | Noncompliant Patients | ||||
|---|---|---|---|---|---|---|---|
| Â | Number of Patients | Endpoint Rate | Number of Endpoints | New Noncompliant Patients | Number of Patients | Endpoint Rate | Number of Endpoints |
1 | 10,000 | 0.1000 | 1,000 | Â | 1,250 | 0.2000 | 250 |
| Â | Â | Â | Â | 1000 | Â | Â | Â |
2 | 8,000 | 0.0125 | 100 | Â | 2,000 | 0.0250 | 50 |
| Â | Â | Â | Â | 878 | Â | Â | Â |
3 | 7,022 | 0.0100 | 70 | Â | 2,828 | 0.0200 | 57 |
Total | Â | Â | 1,170 | Â | Â | Â | 357 |