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Table 1 Results of four hypothetical placebo-controlled (1–4) and two active treatment-controlled (5 and 6) studies: number of events/number of patients in each group.

From: Pooling, meta-analysis, and the evaluation of drug safety

Study

New drug

Placebo-controls

Active-treatment controls

Relative Risk

1

2/60

2/60

1.0

2

9/400

5/400

1.8

3

10/500

5/500

2.0

4

13/500

7/500

 

1.6

5

5/1000

2/1000

2.5

6

6/1000

3/1000

2.0