Table 3 Effects of thiazolidinedione insulin sensitizers
From: Clinical significance of cardiovascular dysmetabolic syndrome
↓ | Insulin resistance |
↓ | Hyperinsulinemia |
↓ | Fasting blood sugar in type 2 diabetes mellitus |
↓ | Free fatty acids |
↓ | Triglycerides |
↑ | High-density lipoprotein cholesterol |
↓ | Plasminogen activator inhibitor-1 activity |
↑ | Vascular compliance |
↓ | Blood pressure/vascular resistance |
↓ | Macrophage inflammatory activity |
Direct vascular effects | |