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Table 2 Post-Event Pharmacologic Treatment of Participants With and Without Heart Failure

From: Validation of Heart Failure Events in the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) Participants Assigned to Doxazosin and Chlorthalidone

 

Hospitalized Heart Failure*

Treated, Nonhospitalized Heart Failure*

Without Heart Failure

 

C

D

C

D

C

D

No. of participants

232

281

93

145

14493

8347

Post-event medication

      

   Blinded medication, (%)

83 (35.8)

126 (44.8)

54 (58.1)

93 (64.1)

11247 (77.6)

6096 (73.0)

   Open-label diuretic (%)

135 (58.2)

180 (64.0)

57 (61.3)

98 (67.6)

1279 (8.8)

1153 (13.8)

   Open-label ACE-inhibitor (%)

90 (38.8)

114 (40.5)

31 (33.3)

44 (30.3)

1154 (8.0)

826 (9.9)

   Open-label beta-blocker (%)

33 (14.2)

38 (13.5)

18 (19.4)

32 (22.1)

3149 (21.7)

2016 (24.0)

   Open-label diuretic, ACE-inhibitor or beta-blocker (%)

169 (72.8)

210 (74.8)

72 (77.4)

119 (82.1)

4829 (33.3)

3347 (40.1)

  1. C = Chlorthalidone treatment group D = Doxazosin treatment group ACE = Angiotensin converting enzyme *Represents data as of first clinic visit after event. Represents data as of most recent clinic visit. All participants represented have at least one follow-up visit. 355 chlorthalidone and 229 doxazosin participants are excluded due to lack of at least one follow-up visit.