Safety and efficacy of ketorolac in improving the prognosis of acute type A aortic dissection patients: a protocol of a randomized, double-blinded, and placebo-controlled study

Table 1 Participant timeline

	Study period
	Enrolment	Allocation	Post-allocation						Close-out
Timepoint	Before surgery	Before surgery	During surgery	Postoperative day 1	Postoperative day 3	Postoperative day 5	Postoperative day 7	Postoperative day 30	Postoperative day 90
Enrolment
Informed consent	×
Eligibility screen	×
Allocation		×
Randomization		×
Interventions
Tissue samples collection			×
Ketorolac tromethamine		×		×	×
0.9% saline		×		×	×
Assessments:
Vital signs	×		×	×	×	×	×	×	×
Hematology examination	×		×	×	×	×	×	×	×
CTA scan of cervical thoracic and abdominal aorta artery	×							×	×
Chest X-ray				×	×	×	×	×	×
Echocardiography	×				×			×	×
Adverse events	×		×	×	×	×	×	×	×
Complications	×		×	×	×	×	×	×	×

ISSN: 1745-6215