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Table 3 Summary of study characteristics and subject matter

From: Statistical analyses of ordinal outcomes in randomised controlled trials: a scoping review

 

Studies―n (%)

Number of publications

144

Year of publication―n (%)

 

- 2017

23 (16%)

- 2018

24 (17%)

- 2019

21 (15%)

- 2020

30 (21%)

- 2021

30 (21%)

- 2022

16 (11%)

Funding source/s―n (%)a

 

- Public

104 (72%)

- Industry

57 (40%)

- Non-profit

39 (27%)

Journal―n (%)

 

- NEJM

61 (42%)

- JAMA

40 (28%)

- The Lancet

34 (24%)

- BMJ

9 (6%)

Medical condition studied - n (%)

 

- Stroke

39 (28%)

- COVID-19

22 (16%)

- Atopic dermatitis

6 (4%)

- Cardiac arrest

5 (3%)

- Other

73 (51%)

Medical specialty studied―n (%)

 

- Neurology

54 (38%)

- Infectious diseases

22 (16%)

- Dermatology

13 (9%)

- Psychiatry

12 (9%)

- Cardiology

7 (5%)

- Rheumatology

7 (5%)

- Other

26 (18%)

Clinical setting―n (%)

141 (98%)

Adaptive design used ―n (%)‡

58 (40%)

Participants in analysis―median (IQR, range)b

380 (202–803, 21–11016)

  1. aThe total does not add up to the total number of publications as more than one option could be selected
  2. bThe number of participants in the primary analysis could be extracted for 142 studies
  3. ‡We did not include studies in which the stopping rules were not definitive, e.g. if a study reported that the study might stop early for efficacy if the p-value was very small but the ultimate recommendation would be decided by the Data Safety & Monitoring Committee