Table 1 Baseline characteristics
PBCC (n = 70) | ICC (n = 70) | |
|---|---|---|
Maternal baseline characteristics | ||
Age at giving birth (years) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Parity (n) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Smoking during pregnancy | n (%) | n (%) |
Preterm premature rupture of the membranes | n (%) | n (%) |
- Gestational age at occurrence (weeks) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Any administration of antenatal corticosteroids | ||
Mode of delivery: | ||
- Vaginal birth | n (%) | n (%) |
- Caesarean section | n (%) | n (%) |
◦ Indication: | ||
▪ Elective | n (%) | n (%) |
▪ Emergency | n (%) | n (%) |
• Reason: | ||
◦ Fetal distress | n (%) | n (%) |
◦ Failure to progress | n (%) | n (%) |
◦ Maternal indication | n (%) | n (%) |
• Use of general anaesthetics | n (%) | n (%) |
Fetal baseline characteristics | ||
Estimated severity of lung hypoplasia: | ||
- Mild | n (%) | n (%) |
- Moderate | n (%) | n (%) |
- Severe | n (%) | n (%) |
Liver position: | ||
- Intra-abdominal | n (%) | n (%) |
- Intrathoracic | n (%) | n (%) |
Observed to expected lung-to-head ratio (%) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
- Gestational age at measurement (weeks) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Fetal lung volume right lung (ml) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Fetal lung volume left lung (ml) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Observed to expected fetal lung volume (%) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
- Gestational age at measurement (weeks) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Fetoscopic endoluminal tracheal occlusion therapy | n (%) | n (%) |
- Duration of tracheal occlusion (days) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Neonatal baseline characteristics | ||
Sex: | ||
- Male | n (%) | n (%) |
- Female | n (%) | n (%) |
Birth weight (g) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Gestational age at birth (weeks) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Apgar score at 1 min | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Apgar score at 5 min | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Umbilical artery pH | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Intubation in the delivery room | ||
- Conventional mechanical ventilation | n (%) | n (%) |
- High frequency oscillatory ventilation | n (%) | n (%) |
◦ Mean airway pressure (cmH2O) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
◦ Frequency (Hz) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
◦ Amplitude (cmH2O) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Continuous positive airway pressure in the delivery room | n (%) | n (%) |
High flow in the delivery room | n (%) | n (%) |
Initial fraction of inspired oxygen (%) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Maximum fraction of inspired oxygen (%) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Maximum positive end-expiratory pressure (cmH2O) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Maximum peak inspiratory pressure (cmH2O) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Maximum flow (l/min) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Body temperature at admission to the intensive care unit (degrees Celsius) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |
Haemoglobin level at admission to the intensive care unit (mmol/l) | Mean ± SD or median [IQR] | Mean ± SD or median [IQR] |