Visits (± window) | V0 | V1b | V2b | V3 | V4 | V5 | V6 | V7 | V8 | V9 | V10 | V11 | V12 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Day1 | 1 month ± 5 days | 2 months ± 5 days | 3 months ± 15 days | 4 months ± 5 days | 5 months ± 5 days | 6 months ± 30 days | 7 months ± 5 days | 8 months ± 5 days | 9 months ± 5 days | 10 months ± 5 days | 11 months ± 5 days | 12 months ± 30 days | |
Visit duration | 2 h | 1 h | 1 h | 3 h | 1 h | 1 h | 3 h | 1 h | 1 h | 1 h | 1 h | 1 h | 3 h |
Complete ophthalmologic examination (slit lamp examination, IOP measurement, and ETDRS BCVA) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Blood pressure measurement | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Blood tests | ✓a | ✓a | ✓a | ✓a | |||||||||
Fundus photography | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ||
OCT | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Indocyanine green angiography (± fluorescein angiography) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |||||||
Quality of life questionnaire | ✓a | ✓a | ✓a | ✓a | |||||||||
Laser/sham laser | ✓ | ✓ | |||||||||||
Intravitreal anti-VEGF injection | ✓ | ✓ | ✓ | PRN | PRN | PRN | PRN | PRN | PRN | PRN | PRN | PRN | PRN |