From: Fibrinogen Early In Severe Trauma studY (FEISTY): study protocol for a randomised controlled trial
Inclusion criteria: | Â |
 Adult (≥18 years) affected by trauma and |  |
 Judged to have significant haemorrhage or |  |
 Predicted to require significant transfusion with ABC Score ≥2 |  |
 or by treating clinician judgment |  |
Exclusion criteria: | Â |
 Injury judged incompatible with survival |  |
 Previous fibrinogen administration this admission |  |
 Pretrauma centre dedicated fibrinogen replacement |  |
 Known objection to blood products |  |
 Known coagulation disorder |  |
 Pregnancy |  |
 Enrolment in competing study |  |