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Table 2 Clinical outcomes

From: Balanced crystalloids versus saline in the intensive care unit: study protocol for a cluster-randomized, multiple-crossover trial

Outcome

Saline (n =)

Balanced (n =)

Adjusted OR (95% CI)

Adjusted P value

Primary outcome

 Major Adverse Kidney Event within 30 days, n (%)

–

–

–

–

Secondary clinical outcomes

 In-hospital mortality, n (%)

  Before ICU discharge

–

–

–

–

  Before 30 days

–

–

–

–

  Before 60 days

–

–

–

–

 ICU-free days, median [IQR]

–

–

–

–

  Mean ± SD

–

–

  

 Ventilator-free days, median [IQR]

–

–

–

–

  Mean ± SD

–

–

  

 Vasopressor-free days, median [IQR]

–

–

–

–

  Mean ± SD

–

–

  

 RRT-free days, median [IQR]

–

–

–

–

  Mean ± SD

–

–

  

Secondary renal outcomes

 Serum creatinine, mg/dl

  Highest before discharge or day 30, mg/dl, median [IQR]

–

–

–

–

  Change from baseline to highest value, mg/dl, median [IQR]

–

–

–

–

  Final value before discharge or 30 days, mg/dl, median [IQR]

–

–

–

–

   Among survivors, mg/dl, median [IQR]

–

–

–

–

  Final creatinine ≥200% baseline, n (%)

–

–

–

–

   Among survivors to hospital discharge

–

–

–

–

   Among survivors to hospital discharge without new RRT

–

–

–

–

Acute kidney injury, stage 2 or higher, n (%)

–

–

–

–

  Developing after enrollment

–

–

–

–

 Receipt of new RRT, No. (%)

–

–

–

–

  Duration of in-hospital receipt, days, median [IQR]

–

–

–

–

  Continued receipt after hospital discharge, n (%)

–

–

–

–

  1. ICU Intensive care unit, RRT Renal replacement therapy