Outcome | Saline (n =) | Balanced (n =) | Adjusted OR (95% CI) | Adjusted P value |
---|---|---|---|---|
Primary outcome | ||||
 Major Adverse Kidney Event within 30 days, n (%) | – | – | – | – |
Secondary clinical outcomes | ||||
 In-hospital mortality, n (%) | ||||
  Before ICU discharge | – | – | – | – |
  Before 30 days | – | – | – | – |
  Before 60 days | – | – | – | – |
 ICU-free days, median [IQR] | – | – | – | – |
  Mean ± SD | – | – |  |  |
 Ventilator-free days, median [IQR] | – | – | – | – |
  Mean ± SD | – | – |  |  |
 Vasopressor-free days, median [IQR] | – | – | – | – |
  Mean ± SD | – | – |  |  |
 RRT-free days, median [IQR] | – | – | – | – |
  Mean ± SD | – | – |  |  |
Secondary renal outcomes | ||||
 Serum creatinine, mg/dl | ||||
  Highest before discharge or day 30, mg/dl, median [IQR] | – | – | – | – |
  Change from baseline to highest value, mg/dl, median [IQR] | – | – | – | – |
  Final value before discharge or 30 days, mg/dl, median [IQR] | – | – | – | – |
   Among survivors, mg/dl, median [IQR] | – | – | – | – |
  Final creatinine ≥200% baseline, n (%) | – | – | – | – |
   Among survivors to hospital discharge | – | – | – | – |
   Among survivors to hospital discharge without new RRT | – | – | – | – |
Acute kidney injury, stage 2 or higher, n (%) | – | – | – | – |
  Developing after enrollment | – | – | – | – |
 Receipt of new RRT, No. (%) | – | – | – | – |
  Duration of in-hospital receipt, days, median [IQR] | – | – | – | – |
  Continued receipt after hospital discharge, n (%) | – | – | – | – |