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Abbreviations: T-1 enrollment, T0 baseline, T1 intermediate, T2 end of treatment, T3 3-month follow-up, EPC endothelial progenitor cell, CEC circulating endothelial cells, T-reg immunological rare cell populations, ANGPT angiopoietin, BDNF Brain Derived Neurotrophic Factor, BMP Bone Morphogenetic Protein, dPAPP-A Pregnancy-associated Plasma Protein A, EGF Epidermal Growth Factor, ET endothelin, FGF Fibroblast Growth Factor, FST follistatin, G- granulocyte, GM- granulocyte-macrophage, CSF Colony Stimulating Factor, HB-EGF Heparin-binding EGF-like growth factor, HGF Hepatocyte Growth Factor, IFN interferon, IL interleukin, ra receptor antagonist, IP-10 10 kDa-interferon gamma-induced protein, MCP-1 Monocyte Chemoattractant Protein 1, MIP-1α C-C motif chemokine 3, MPO myeloperoxidase, NCAM Neural Cell Adhesion Molecule, PAI Plasminogen Activator Inhibitor, PDGF Platelet-derived Growth Factor, Pecam Platelet and Endothelial Cell Adhesion Molecule, PLGF Placenta growth factor, PTX pentraxin, RANTES C-C motif chemokine ligand 5, sE-Selectin Soluble Endothelial Leukocyte Adhesion Molecule, S-ICAM Soluble Intercellular Adhesion Molecule, s-VCAM Soluble Vascular Cell Adhesion Molecule, TF Tissue Factor, TNF Tumor Necrosis Factor, VEGF Vascular Endothelial Growth Factor, GSH/GSSG reduced glutathione/oxidized glutathione ratio
