From: The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine
Data source | ||||||||
---|---|---|---|---|---|---|---|---|
Patient surveys | Patient interviews | Physician surveys | Physician interviews | Physician checklist | Audio recordings | EHR review | GRC logbook | |
Attitudes and preferences | ||||||||
Attitudes about project[48] | ✓ | ✓ | ✓ | |||||
Attitudes about sequencing[13] | ✓ | ✓ | ✓ | |||||
Perceived utility | ✓ | ✓ | ✓ | ✓ | ✓ | |||
Preferences for information | ✓ | ✓ | ||||||
Understanding | ||||||||
✓ | ✓ | ✓ | ✓ | ✓ | ||||
Understanding of results | ✓ | ✓ | ✓ | |||||
Genetic self-efficacy[51] | ✓ | ✓ | ||||||
Genetic literacy[52] | ✓ | ✓ | ✓ | ✓ | ||||
Health and risk perceptions[53] | ✓ | |||||||
Psychological impact | ||||||||
General anxiety and depression[30] | ✓ | |||||||
Results-specific affect[54] | ✓ | |||||||
Intolerance of uncertainty[55] | ✓ | |||||||
Behavioral impact | ||||||||
Health behaviors and intentions[56] | ✓ | ✓ | ✓ | |||||
Insurance coverage[57] | ✓ | ✓ | ||||||
Medication and supplement use | ✓ | ✓ | ✓ | ✓ | ||||
Information seeking and sharing[58] | ✓ | ✓ | ✓ | ✓ | ✓ | |||
Health-care utilization | ||||||||
Willingness to pay | ✓ | ✓ | ||||||
Shared decision-making[59] | ✓ | ✓ | ✓ | ✓ | ||||
Follow-up testing and screening[60] | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
Decisional satisfaction | ||||||||
Satisfaction[61] | ✓ | ✓ | ✓ | |||||
Decisional regret[62] | ✓ | ✓ | ✓ | |||||
Expectations | ✓ | ✓ | ✓ |