| Activities | Sleep | Non-nose/non-eye symptoms | Practical problems | Nasal symptoms | Eye symptoms | Emotional | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Slope | MD | Slope | MD | Slope | MD | Slope | MD | Slope | MD | Slope | MD | Slope | MD | |
(SE) | ( P) | (SE) | ( P) | (SE) | ( P) | (SE) | ( P) | (SE) | ( P) | (SE) | ( P) | (SE) | ( P) | |
T2 | Â | |||||||||||||
CS vs. placebo | 2.02 (0.95) | -2.86 (0.004) | 1.78 (0.96) | -2.04 (0.04) | 6.39 (2.13) | -7.95 (<0.0005) | 3.77 (1.17) | -3.21 (0.006) | 3.43 (1.43) | -3.49 (0.02) | 2.93 (1.21) | -2.90 (0.02) | 2.80 (1.15) | -3.67 (0.001) |
CS vs. YS | -0.31 (0.95) | -0.38 (0.69) | 0.47 (0.96) | -0.30 (0.76) | 2.95 (2.12) | -2.69 (0.20) | 1.10 (1.17) | -0.49 (0.68) | 0.69 (1.43) | -0.02 (0.99) | 0.96 (1.21) | -0.69 (0.57) | 0.75 (1.15) | -1.47 (0.20) |
YS vs. placebo | 2.33 (0.95) | -3.24 (0.002) | 1.31 (0.97) | -1.74 (0.07) | 3.44 (2.13) | -5.26 (0.01) | 2.68 (1.17) | -2.72 (0.02) | 2.745 (1.44) | -3.47 (0.02) | 1.98 (1.22) | -2.22 (0.07) | 2.05 (1.15) | -2.20 (0.06) |
T3 | Â | |||||||||||||
CS vs. placebo | 2.93 (0.95) | -3.76 (0.001) | 2.75 (0.96) | -3.01 (0.002) | 7.32 (2.13) | -8.88 (<0.0005) | 4.87 (1.17) | -4.31 (<0.0005) | 5.44 (1.43) | -5.50 (<0.0005) | 3.22 (1.21) | -3.20 (0.008) | 3.01 (1.15) | -3.97 (0.001) |
CS vs. YS | 0.81 (0.95) | -0.74 (0.44) | 1.38 (0.96) | -1.21 (0.21) | 3.08 (2.12) | -2.82 (0.18) | 2.07 (1.17) | -1.46 (0.21) | 2.98 (1.43) | -2.30 (0.11) | 1.47 (1.21) | -1.20 (0.32) | 0.35 (1.15) | -1.06 (0.36) |
YS vs. placebo | 2.12 (0.95) | -3.03 (0.003) | 1.38 (0.97) | -1.80 (0.06) | 4.24 (2.13) | -6.06 (0.004) | 2.81 (1.17) | -2.85 (0.02) | 2.47 (1.44) | -3.20 (0.03) | 1.76 (1.22) | -2.00 (0.10) | 2.76 (1.15) | -2.91 (0.01) |
T4 | Â | |||||||||||||
CS vs. placebo | 3.18 (0.95) | -4.01 (<0.0005) | 3.47 (0.96) | -3.73 (<0.0005) | 6.20 (2.13) | -7.76 (<0.0005) | 5.29 (1.17) | -4.73 (<0.0005) | 6.70 (1.43) | -6.76 (<0.0005) | 3.55 (1.21) | -3.52 (0.004) | 3.17 (1.15) | -4.04 (<0.0005) |
CS vs. YS | 0.25 (0.95) | -0.18 (0.85) | 1.29 (0.96) | -1.13 (0.24) | 1.61 (2.12) | -1.35 (0.53) | 1.37 (1.17) | -0.76 (0.52) | 2.91 (1.43) | -2.24 (0.12) | 1.18 (1.21) | -0.91 (0.70) | 0.19 (1.15) | -0.91 (0.43) |
YS vs. placebo | 2.93 (0.95) | -3.83 (0.001) | 2.18 (0.97) | -2.60 (0.007) | 4.59 (2.13) | -6.41 (0.003) | 3.92 (1.17) | -3.97 (0.001) | 3.79 (1.44) | -4.52 (0.002) | 2.36 (1.22) | -2.61 (0.03) | 2.97 (1.15) | -3.12 (0.007) |