Prognosis after ST-elevation myocardial infarction: a study on cardiac magnetic resonance imaging versus clinical routine

Table 2 Traditional outcome markers and CMR parameters: association with MACE in univariable and stepwise multivariable Cox regression analysis

	Univariable analysis		Multivariable analysis
Variable	HR (95% CI)	P value	HR (95% CI)	P value
Male gender	0.97 (0.53–1.77)	0.97	not included	-
Hyperlipidemia	1.42 (0.82–2.47)	0.21	not included	-
Serum creatinine, μmol/l	1.01 (0.99–1.02)	0.23	not included	-
CK-MB_max, μmol/l	1.02 (1.01–1.03)	0.01	-	-
TIMI-risk score	1.27 (1.15–1.41)	<0.001	-	-
ST-segment resolution, %	0.98 (0.97–0.99)	0.001	-	-
TIMI-flow pre-PCI 0	1.24 (1.01–1.53)	0.04	-	-
TIMI-flow post-PCI 0-II	2.49 (1.44–4.31)	0.001	-	-
LV-EF_echo, %	0.95 (0.92–0.97)	<0.001	-	-
Time-to-revascularization, min	1.00 (0.99–1.01)	0.44	not included	-
LV-EF_CMR, %	0.96 (0.94–0.97)	<0.001	-	-
Infarct size, %LV	1.07 (1.05–1.09)	<0.001	-	-
MO, %LV	1.16 (1.07–1.25)	<0.001	-	-
MSI	0.93 (0.92–0.95)	<0.001	0.94 (0.92–0.96)	<0.001

%LV = percentage of left ventricular mass; CK-MB_max = maximum level of creatine kinase-MB; CI = confidence interval; CMR = cardiac magnetic resonance imaging; HR = hazard ratio; LV-EF_CMR = left ventricular ejection fraction assessed by CMR; LV-EF_echo = left ventricular ejection fraction assessed by echocardiography; MACE = major adverse cardiac events; MO = microvascular obstruction; MSI = myocardial salvage index; PCI = percutaneous coronary intervention; TIMI = Thrombolysis In Myocardial Infarction.

ISSN: 1745-6215