Combination of inositol and alpha lipoic acid in metabolic syndrome-affected women: a randomized placebo-controlled trial

Table 1 Anthropometric and metabolic features of the study groups: inositol + alpha lipoic acid (n = 77), placebo (n = 78)

	Ino + α T0	Plac T0	Ino + α T6	Plac T6	Ino + α vs Pla P T0	Ino + α vs Pla P T6	P Ino + α T0 vs T6	P Plac T0 vs T6
Age	57.71 ± 7.9	58.2 ± 5.6
BMI, kg/m²	30.35 ± 5.3	29.21 ± 4.8	28.46 ± 6.2	28.34 ± 5.7	0.1	0.7	<0.0001	0.002
WC cm	97.15 ± 10	99.23 ± 8	92.34 ± 9	97 ± 7	0.08	0.1	<0.000	0.0001
WHR	0.87 ± 0.06	0.89 ± 0.02	0.79 ± 0.04	0.81 ± 0.03	0.1	<0.0001	<0.000	0.0001
Glucose, mg/dl	106 ± 19.58	107 ± 20.13	95 ± 21.56	102 ± 21.79	0.64	<0.0001	<0.000	0.03
Insulin, mmol/L	15.53 ± 8.08	13.74 ± 7.04	8.51 ± 5.11	11.98 ± 6.88	<0.0001	<0.0001	<0.000	0.08
HOMA-IR	4.06 ± 2.44	4.02 ± 1.61	2.74 ± 1.53	3.99 ± 1.22	0.0001	<0.0001	<0.000	0.01
HDL-C, mg/dl	42.30 ± 13.42	40.46 ± 12.45	48.80 ± 14.79	41.72 ± 15.13	0.8	<0.0001	<0.000	0.9
Chol-tot mg/dl	214.63 ± 42.56	203.08 ± 32.71	202.92 ± 49.72	202.01 ± 30.51	0.2	<0.0001	<0.0001	0.3
Triglycerides, mg/dl	111.18 ± 46	112.23 ± 49	90.37 ± 34.36	109.78 ± 48	<0.0001	<0.0001	<0.0001	0.4

Values are means ± SD. Ino + α, inositol plus alpha lipoic acid; T0, time 0; Plac, placebo; T6, 6 months; P, P value. BMI, body mass index; WC, waist circumference; WHR, waist-hip ratio; HOMA-IR homeostasis model assessment ratio-insulin resistance; HDL-C, high-density lipoprotein cholesterol; Chol-tot, total cholesterol; SD, standard deviation.

ISSN: 1745-6215