Non-primary publication (n = 69) | Primary publication (n = 69) | |
---|---|---|
Journal type | ||
Specialty | 56 (81%) | 22 (32%) |
General | 13 (19%) | 47 (68%) |
Funding source | ||
Solely industry | 14 (20%) | 21 (30%) |
Part industry | 17 (25%) | 23 (33%) |
Non industry | 31 (45%) | 25 (36%) |
Unknown | 7 (10%) | 0 |
Trial registration | ||
Reported | 30 (43%) | 32 (46%) |
Not reported | 39 (57%) | 37 (54%) |
Trial protocol | ||
Reported | 27 (39%) | 26 (38%) |
Not reported | 42 (61%) | 43 (62%) |
Study centers | ||
Single | 1 (2%) | 3 (4%) |
Multiple | 56 (81%) | 64 (93%) |
Unclear | 12 (17%) | 2 (3%) |
Time period assessed | ||
Reported | 39 (57%) | 64 (93%) |
Not reported | 30 (43%) | 5 (7%) |
Number of study groups | ||
2 | 55 (80%) | 54 (78%) |
3 | 10 (14%) | 12 (17%) |
4 | 3 (4%) | 2 (3%) |
≥5 | 1 (2%) | 1 (2%) |
Number of patients randomized | ||
Median (IQR) | 1,003 (347 to 2,699) | 1,452 (389 to 4,439) |
Range | 34 to 21,906 | 34 to 21,906 |