Table 2 Reporting of non-primary publication study outcomes and results
Overall (n = 69) | Comparison as randomized (n = 42) | Comparison not as randomized (n = 27) | |
|---|---|---|---|
Number of outcomes reported in non-primary publicationa | |||
1 to 5 | 29 (42%) | 20 (48%) | 9 (33%) |
6 to 10 | 11 (16%) | 5 (12%) | 6 (22%) |
11 to 20 | 11 (16%) | 6 (14%) | 5 (19%) |
>20 | 11 (16%) | 8 (19%) | 3 (11%) |
Unclear | 7 (10%) | 3 (7%) | 4 (15%) |
Outcomes reported in non-primary publication | |||
Pre-specified | 22 (32%) | 16 (38%) | 6 (22%) |
Exploratory | 10 (15%) | 7 (17%) | 3 (11%) |
Pre-specified and exploratory | 5 (7%) | 2 (5%) | 3 (11%) |
32 (46%) | 17 (40%) | 15 (56%) | |
Unclear | |||
Analysis for main outcome of non-primary publication | |||
Pre-specified (in publication) | 16 (23%) | 12 (28.5%) | 4 (15%) |
5 (7%) | 5 (12%) | 0 | |
Pre-specified (in register) | 19 (28%) | 13 (31%) | 6 (22%) |
Exploratory | 29 (42%) | 12 (28.5%) | 17 (63%) |
Unclear | |||
Statistical methods used to compare groups for main outcome of non-primary publication | |||
Reported | 68 (98%) | 42 (100%) | 26 (96%) |
Not reported | 1 (2%) | 0 | 1 (4%) |
Summary result for each group for main outcome of non-primary publication | |||
Reported | 66 (96%) | 40 (95%) | 26 (96%) |
Not reported | 3 (4%) | 2 (5%) | 1 (4%) |
Estimated effect size and precision of effect estimate for main outcome of non-primary publication | |||
Reported | 52 (75%) | 32 (76%) | 20 (74%) |
Not reported | 17 (25%) | 10 (24%) | 7 (26%) |
Results statistically significant for main outcome of non-primary publication | |||
Yes | 44 (64%) | 23 (55%) | 21 (78%) |
No | 21 (30%) | 15 (35%) | 6 (22%) |
Unclear | 2 (3%) | 2 (5%) | 0 |
Not reported | 2 (3%) | 2 (5%) | 0 |